This book offers an updated review of the physiology of the carotid body chemoreceptors. It provides the trends in the field as it contains results in the topics that are at the frontiers of future developments in O2-sensing in chemoreceptor cells.
The Discovery of Sensory Nature of the Carotid Bodies. Invited Article; F. De Castro. Fifty Years of Progress in Carotid Body Physiology. Invited article; R. S. Fitzgerald, C. Eyzaguirre and P. Zapata. Carotid Body: New Stimuli and New Preparations. Invited article; Colin A. Nurse. Enzyme-Linked Acute Oxygen Sensing In Airway And Arterial Chemoreceptors. Invited article; Paul J Kemp & C Peers. Cysteine Residues in the C-terminal tail of the Human BKCaa Subunit are Important for Channel Sensitivity to Carbon Monoxide; S.P. Brazier, V. Telezkhin, R. Mears, C.T. M?ller, D. Riccardi and P.J. Kemp. Modulation of O2 Sensitive K+ Channels by AMP-activated Protein Kinase; M.L Dallas, J.L Scragg, C.N. Wyatt, F. Ross, D.G Hardie, A.M Evans and C Peers. Hydrogen Sulfide Inhibits Human BKCa Channels; V. Telezhkin, S. P. Brazier, S. Cayzac, C. T. M?ller, D. Riccardi and D P. J. Kemp. DPPX Modifies TEA Sensitivity of the Kv4 Channels in Rabbit Carotid Body Chemoreceptor Cells; O. Colinas, F.D. P?rez-Carretero, E. Alonso, J.R. L?pez-L?pez and M. T. P?rez-Garc?a. Sustained Hypoxia Enhances TASK-like Current Inhibition by Acute Hypoxia in Rat Carotid Body Type-I Cells; F. Ortiz, R. Iturriaga and R. Varas. Inhibition of L-type Ca2+ Channels by Carbon Monoxide; M.L. Dallas, J.L. Scragg and C. Peers. Effects of the Polyamine Spermine on Arterial Chemo-Reception; S. Cayzac, A. Rocher, A. Obeso, C. Gonz?lez, P.J. Kemp and D. Riccardi. RT-PCR and Pharmacological Analysis of L-and T-Type Calcium Channels in Rat Carotid Body; A.I. C?ceres, E. Gonz?lez-Obeso, C. Gonz?lez and A. Rocher. Functional characterization of phosphodiesterases 4 in the rat carotid body: effect of oxygen concentrations; A.R. Nunelƒ5