Basis and Treatment of Cardiac Arrhythmias [Hardcover]

History of Arrhythmias.- Pacemaker Current and Automatic Rhythms: Toward a Molecular Understanding.- Proarrhythmia.- Cardiac Na+ Channels as Therapeutic Targets for Antiarrhythmic Agents.- Structural Determinants of Potassium Channel Blockade and Drug-Induced Arrhythmias.- Sodium Calcium Exchange as a Target for Antiarrhythmic Therapy.- A Role for Calcium/Calmodulin-Dependent Protein Kinase II in Cardiac Disease and Arrhythmia.- AKAPs as Antiarrhythmic Targets?.- ?-Blockers as Antiarrhythmic Agents.- Experimental Therapy of Genetic Arrhythmias: Disease-Specific Pharmacology.- Mutation-Specific Pharmacology of the Long QT Syndrome.- Therapy for the Brugada Syndrome.- Molecular Basis of Isolated Cardiac Conduction Disease.- hERG Trafficking and Pharmacological Rescue of LQTS-2 Mutant Channels.DE