Biopharmaceutical Drug Design and Development [Hardcover]

This book provides a comprehensive examination of the newest biopharmaceutical drugs. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, and contains a review of the Human Genome Project.

Biopharmaceutical Drug Design and Development, Second Edition, furthers the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since that time. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel to a discussion on the dynamic, exciting field of biotechnology.

Biopharmaceutical Drug Design and DevelopmentSecond Edition1. Biotechnology: 2005 and Beyond2. Human Genome Project3. Bioinformatics4. DNA Microarrays in Drug Discovery and Development5. Microarray Technology Using Proteins, Cells, and Tissues6. Pharmacogenetic Issues in Biopharmaceutical Drug Development7. Transgenics8. Therapeutic Gene Delivery9. Stem Cells10. Nucleic Acid Based Therapeutics11. Therapeutic Strategies Targeting the Innate Immune Response12. Pharmacogenetics in the Clinic13. Molecular Modeling: Considerations for the Design ofPharmaceuticals and Biopharmaceuticals14. Macromolecular Drug Delivery15. Changl]