Biorenewable Solvents for Organic Synthesis [Paperback]

In this brief the authors introduce a series of recently developed bio-based solvents including cyclopentyl methyl ether (CPME),  ?-valerolactone (GVL), 2-methyl tetrahydrofuran (2-MeTHF), propylene carbonate (PC), and cyrene.  Traditional organic solvents used for organic synthesis (such as benzene, ether, chloroform) have a series drawbacks on toxicity, environmental impact, and safely related issues. In addition, the fossil fuel-derived organic solvents are not sustainable. Therefore the development of biorenewable solvents is a topic of current interest. For each of the solvents, their production, toxicity profile, renewable pathway, and their utility in organic synthesis, biosynthesis, and separation processes is discussed. The target audiences of this book are organic and medicinal chemists with interests in using green solvents. It can also be used as a reference for undergraduate and graduate courses related to organic and green chemistry.

 Introduction of biorenewable solvents.- Biorenewable solvents.- Cyclopentyl methyl ether (CPME).- ?-alerolactone (GVL).- 2-Methyl tetrahydrofuran (2-MeTHF).- Glycerine carbonate (GC).- Propylene Carbonate (PC).- Cyrene.- Other solvent.-Conclusive Remarks.

Dr. Wei Zhang is a Professor and the Director of the Center for Green Chemistry at the University of Massachusetts Boston. He received his PhD and did his post-doctoral research at the University of Pittsburgh.  His previous positions include Research Assistant Professor at the University of Pittsburgh, Senior Chemist at DuPont, and Director at Fluorous Technologies, Inc. Prof. Zhang's research is in the areas of fluorous chemistry, organocatalysis, medicinal chemistry, and green chemistry. He has coauthored over 250 papers including three in Chem. Rev., co-edited Green techniques for organic and medicinal applications (Wiley 2012 & 2018), and&lã.