This 1992 text served as a regular forum for evaluation and dissemination of information in the neurobiological basis of psychiatric disorder.When it was first published in 1991, Neurobiology and Psychiatry served as a regular forum for evaluation and dissemination of information in the neurobiological basis of psychiatric disorder. At the time of publication, this fundamental field of biological psychiatry was a rapidly expanding field of study.When it was first published in 1991, Neurobiology and Psychiatry served as a regular forum for evaluation and dissemination of information in the neurobiological basis of psychiatric disorder. At the time of publication, this fundamental field of biological psychiatry was a rapidly expanding field of study.This book was originally published in 1992. At the time of publication, the neurobiological basis of psychiatric disorder was a rapidly expanding field of study, primarily as a result of developments in the basic neurosciences. Neurobiology and Psychiatry served as a regular forum for evaluation and dissemination of information in this fundamental field of biological psychiatry. Topics selected for review illustrated the application of a range of neurobiological techniques to major psychiatric disorders, providing an in-depth review of work in this field. The intended readership included established research workers in the field, postgraduate psychiatrists, psychiatric trainees and other clinical and laboratory workers.Contributors; Editors' preface; 1. Post-mortem neurochemistry of schizophrenia M. C. Royston and M. D. C. Simpson; 2. Temporal lobe pathology and schizophrenia G. W. Roberts; 3. Frontal lobe, structure, function and connectivity in schizophrenia J. M. Gold and D. R. Weinberger; 4. Neurotransmitter system abnormalities associated with the neuropathology of Alzheimer's disease D. Dewar; 5. Molecular neuropathology of Alzheimer's disease M. Goedert, M. C. Potier and M. G. Millantini; 6. Neurochemical studies ofl³¾