Part I. AntimutagensInducers of Enzymes That Protect Against Carcinogens and Oxidants: Drug- and Food-Based Approaches with Dithiolethiones and SulforaphaneThomas W. Kensler and Paul TalalayChemoprevention by IsothiocyanatesStephen S. HechtAntigenotoxic and Cancer Preventive Mechanisms of N-Acetyl-l-CysteineSilvio De Flora, Alberto Izzotti, Adriana Albini, Francesco D'Agostini, Maria Bagnasco, and Roumen BalanskyModifiers of Cytochrome(s) P450John DiGiovanni and Heather E. KleinerPart II. AntiinflammatoriesAntiinflammatories and Chemoprevention: NSAIDs and Other Inhibitors of Arachidonic Acid MetabolismGary B. Gordon, Gary J. Kelloff, and Caroline C. SigmanCyclooxygenase-2 Inhibitors and Colorectal Cancer PreventionRaymond N. DuBoisLipoxygenases as Targets for Cancer PreventionSusan M. Fischer and Russell D. KleinInducible Nitric Oxide Synthase as a Target for ChemopreventionLorne J. Hofseth, Tomohiro Sawa, S. Perwez Hussain, and Curtis C. HarrisChemoprevention of Cancer of the Respiratory Tract by Agents Delivered by Aerosol: Applications to Glucocorticoids and 5-FluorouracilTimothy S. Wiedmann and Lee W. WattenbergChemoprevention of Cancer by CurcuminBandaru S. Reddy and Chinthalapally V. RaoProstacyclin and Lung Cancer ChemopreventionRobert L. Keith, York E. Miller, Paul A. Bunn Jr., Patrick Nana-Sinkam, Raphael A. Nemenoff, and Mark W. GeraciPart III. Nuclear Receptor SuperfamilyNuclear Receptor Superfamily: Targets for ChemopreventionJulia A. Lawrence and Kapil DhingraA. AntiandrogensProstate Cancer Chemoprevention: 5a-Reductase InhibitorsJennifer E. Drisko and Siu-Long YaoSearching for SARA: The Role of Selective Androgen-Receptor Antagonists in Prostate CancerMark S. Chapman,William Y. Chang, Andr?s Negro-Vilar, and Jeffrey N. MinerB. AntiestrogensAromatase Inhibitors as Chemopreventives of Breast CancerMitchell Dowsett and Judy E. GarberBreast Cancer Chemoprevention by Selective Estrogen Receptor ModulatorsCarolyn L. SmithC. Natural Vitamin D and Synthetic Alc