Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading experts will present up-to-date overviews about cell fusion in physiological and patho-physiological processes, which further covers the current knowledge about cell fusion-mediating molecules. Volume 1 deals with Cell Fusion in Health and will cover aspects of cell fusion in fertilization, placentation, in C. elegans, in skeletal muscle development and tissue repair, and the use of cell fusion for cellular reprogramming and cancer vaccine development. Volume 2 focuses on Cell Fusion in Disease with a particular emphasis on the role of cell fusion in cancer development and progression. Thus, Cell Fusion in Health and Disease Vol 1 & Vol 2 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion and beyond.This 2-volume set covers the processes of cell fusion in health and disease, including fertilization, placentation, and cell fusion in cellular reprogramming and cancer vaccine development, and on the role of cell fusion in cancer development and progression.
Preface, Thomas Dittmar, Kurt S. Z?nker (Witten/ Herdecke University, Witten, Germany); 1 Introduction, Thomas Dittmar, Kurt S. Z?nker (Witten/ Herdecke University, Witten, Germany); 2 Heterochronic control of AFF-1-mediated cell-to-cell fusion in C. Elegans, Lilach Friedlander-Shani, Benjamin Podbilewicz (Israel Institute of Technology, Haifa, Israel); 3 Role of SNAREs in membrane fusion, Bahnu P. Jena (Wayne State University School of Medicine, Detroit, MI, USA); 4 Molecular and cellular mechanisms of mammalian cell fusion, Xiaofeng Zhou, Jeffrey L. Platt (University of Michigan, Ann Arbor, MI, USA); 5 Membrane fusions during mlĂ*