Analogous to genomics, which defines all genes in a genome irrespective of their functionality, metabolomics seeks to profile all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.
Metabolomics has the potential of defining cellular processes as it provides a measure of the ultimate phenotype of an organism, as defined by the collage of small molecules, whose levels of accumulation is altered in response to genetic and environmentally induced changes in gene expression.
This book presents a guide for new practitioners of metabolomics, providing insights as to the current use and applications of metabolomics.
Validated High Quality Automated Metabolome Analysis of Arabidopsis Thaliana Leaf Disks.- GC-MS Peak Labeling Under ArMet.- Metabolomics and Plant Quantitative Trait Locus Analysis The Optimum Genetical Genomics Platform?.- Design of Metabolite Recovery by Variations of the Metabolite Profiling Protocol.- ncovering the Plant Metabolome: Current and Future Challenges.- Lipidomics: ESI-MS/MS-Based Profiling to Determine the Function of Genes Involved in Metabolism of Complex Lipids.- Time-Series Integrated Metabolomic and Transcriptional Profiling Analyses.- Metabolomics of Cuticular Waxes: A System for Metabolomics Analysis of a Single Tissue-Type in a Multicellular Organism.- Metabolic Flux Maps of Central Carbon Metabolismin Plant Systems.- MetNet: Systems Biology Tools for Arabidopsis.- Identification of Genes Involved in Anthocyanin Accumulation by Integrated Analysis of Metabolome and Transcriptome in Pap1-Overexpressing Arabidopsis Plants.- Identifying Substrates and Products of Enzymes of Plant Volatile Biosynthesis with the Help of Metabolic Profiling.- Profiling Diurnal Changes in Metabolite and Transcript Levels in Potato Leaves.- Gene Expression and Metabolic Analysis Reveal that the Phytotoxin Coronal£+