Desmopressin in Bleeding Disorders [Paperback]

I. Hemostasis and Desmopressin.- Regulation of Haemostasis: The Role of Arginine Vasopressin.- Von Willebrand Factor and P-Selectin Targeting to and Release from Endothelial Cell-Specific Storage Granules.- Factor VIII in Monkeys, Effect of DDAVP Analogues.- Possible Involvement of Serotonin in the Haemostatic Action of DDAVP in Patients with Uraemia.- Molecular Mechanisms of Cellular Responses to DDAVP.- II. Phemacology and Pharmacodynamics of Desmopressin.- Some Pharmacological Properties of Desmopressin.- Pharmacokinetics of Desmopressin.- Fall-Off of Factor VIII Elicited by Desmopressin Administration in Hemophiliacs and von Willebrands Disease Patients.- Toxicity of Desmopressin and Related Peptides.- The Hemodynamic and Coagulant Effects of dDAVP are Specific Extrarenal V2-Receptor Responses.- The Vasopressin Antagonist SK&F 105494 Inhibits Desmopressin-Stimulated Clotting Factor Release in vivo.- Non-Responsivess of t-PA, u-PA, and vWF to DDAVP.- III. Desmopressin in Renal Disease.- Control of Bleeding in Uremic Patients.- Hemostatic Effectiveness of Desmopressin in the Bleeding Disorders of Uremia.- Renal Function and Thromboembolism in High Dose Desmopressin Treatment.- IV. Desmopressin and Platelets.- DDAVP Corrects the Platelet Dysfunction Produced by Cardiopulmonary By-Pass, Hemodialysis and Prolonged Storage: Re-Expresion of Glycoprotein Ib on the Platelet Membrane.- Desmopressin in the Treatment of Congenital and Acquired Defects of Platelet Functions.- The Effectiveness of Desmopressin in Patients with Disorders of Primary Haemostasis.- Clinical Efficacy of Desmopressin and Consistency of Responses to Separate Infusion in Patients with Prolonged Bleeding Time Due to Congenital Platelet Defect.- V. Desmopressin and Surgery.- Desmopressin, von WillebrandFactor and Surgery.- Desmopressin in Cardiac Surgery with Extra-Corporeal Circulation.- Desmopressin Corrects the Hemostatic Disorder Induced by Dextran and Regional Anesthesia in Total Hip Replacemlã4