Diseases of DNA Repair [Hardcover]

Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer. The purpose of this book is to present an updated detailed account of some important additional diseases of DNA repair. It has not been possible to cover all the DNA repair deficient diseases in this volume, hence diseases such as Blooms syndrome, Werners syndrome, Nijmegen breakage syndrome, ataxia telangiectasialike disorder, RA D 50 deficiency, RIDDLE syndrome and others will be presented in a forthcoming volume.

This book presents an updated detailed account of some important additional diseases of DNA repair. It provides brief accounts of the basics of DNA damage, repair, mutagenesis and cancer.?

Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer. The purpose of this book is to present an updated detailed account of some important additional diseases of DNA repair. It has not been possible to cover all the DNA repair deficient diseases in this volume, hence diseases such as Blooms syndrome, Werners syndrome, Nijmegen breakage syndrome, ataxia telangiectasialike disorder, RA D 50 deficiency, RIDDLE syndrome and others will be presented in a forthcoming volume.1. Triple?A SyndromeVijaya Sarathi and Nalini S. ShahAbstractIntroductionEpidemiologyEtiologyPathologyDiagnosisDifferential DiagnosisTreatmentConclusion2. Amyotrophic Lateral SclerosisJ. Jefferson P. Perry, David S. Shin and John A. TainerAbstractIntroductionClinical FeaturesGenetic Basis and the Molecular Mechanism of the DiseaseCu,ZnSl£"