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1. Introduction to the Endothelin System.- 2. Endothelin Receptors and Receptor Antagonists.- 3. Novel Endothelin Receptors.- 4. Sticky Conundrums in the Endothelin System: Unique Binding Characteristics of Receptor Agonists and Antagonists.- 5. Functional Coordination and Cooperation Between Endothelin and Nitric Oxide Systems in Vascular Regulation.- 6. Molecular and Structural Biology of Endothelin Receptors.- 7. Cytokine Regulation of Endothelin Action.- 8. Endothelin Modulation of Renal Sodium and Water Transport.- 9. Endothelin and Ion Channels.- 10. Endothelin and Calcium Signaling.- 11. Endothelin Regulation of Cardiac Contractility: Signal Transduction Pathways.- 12. Endothelin Signaling to the Nucleus: Regulation of Gene Expression and Phenotype.- 13. Mechanisms of Endothelin-induced Mitogenesis and Activation of Stress Response Protein Kinases.- Color Insert.Springer Book ArchivesNLGPSR ComplianceThe European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this.If you have any concerns about our products you can contact us on ProductSafety@springernature.com.In case Publisher is established outside the EU, the EU authorized representative is:Springer Nature Customer Service Center GmbHEuropaplatz 369115 Heidelberg, GermanyProductSafety@springernature.com