Enzymes in Synthetic Organic Chemistry [Paperback]

This book covers the most recent development of enzymatic organic synthesis, with particular focus on the use of isolated enzymes. It is organized into one introductory chapter dealing with the characteristics of enzymes as catalysts, and five chapters dealing with different types of chemical transformations. Methods for enzyme immobilization and stabilizaton, the use of enzymes in extreme environments, and the alteration of enzyme properties by chemical modification and site-directed mutagenesis for synthetic purposes are covered.Chapter headings: General Aspects. Use of Hydrolytic Enzymes: Amidases, Proteases, Esterases, Lipases, Nitrilases, Phosphatases, Epoxide Hydrolases. Oxidoreductions. C-C Bond Formation. Synthesis of Glycoside Bonds. Addition, Elimination and Other Group Transfer Reactions (Phosphoryl-, Methyl-, Sulpho- and Amino-Transfer Reactions).Stanley M. Roberts
In summary this is an important text book written by two persons with outstanding reputations in the field. For a scientist working in the area it is like a good novel - having started to read it you cannot put it down. However, perhaps more importantly, it will serve as an excellent introduction for those persons wishing to get the flavour of the various techniques.
Synthesis
Alan Wiseman
This unique and outstanding book presents a well-documented review of the use of enzymes in recognised areas of organic syntheses.... The wealth of detail is remarkable, and use of the subject index provides access to methods of bioconversion within each category covered by the five chapters. This book is highly recommended to organic chemists who wish to adopt biocatalysts to achieve synthetic specifications, and who require some background information in applied enzymology and enzyme biotechnology.
Chemistry amp; Industry
C.L. Willis
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