Fungal Immunology From an Organ Perspective [Paperback]

A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.

Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases.

This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.

PrefaceContributors Section 1 - Nasal Cavity1. Fungal Sinusitis; Tobias E. Rodriguez, Jack R. Harkema, and Gary B. Huffnagle Section 2 - Oral Cavity2. Innate Defense Mechanisms in Oral Candidiasis; Anna Dongari-Bagtzoglou3. Humoral Factors in the Protection of the Oral Cavity against Candidiasis; Stephen J. Challacombe, Durdana Rahman, Mukesh Mistry, and Julian A. Naglik4. Oral Candidiasis: Clinical Manifestations and Cellular Adaptive Host Responses; Robert B. Ashman and Camile S. Farah Section 3 - Lungs5. The Innate and Adaptive Immune Response to Pulmonary Histoplasma capsulatum Infection; George S. Deepe, Jr.6. Lung Immunity to Blastomyces dermatitidis Infection; Marcel W?thrich and Bruce S. Klein7. Innate Immunity in the Lungs to Cryptococcal Infection; Kazuyoshi Kawakami8. Pulmonary Cell-Mediated Imml£"