Genes and Aging [Paperback]

Genes and Aging is for all students and researchers interested in the molecular biology of aging.The maximum life span of multicellular organisms varies greatly: for a fruitfly it is about 30 days, for a dog about 20 years, and for a human about 100 years The basic cause of aging in these organisms (eukaryotes) lies at the level of genes. This book reviews the biology of the gene in relation to aging.The maximum life span of multicellular organisms varies greatly: for a fruitfly it is about 30 days, for a dog about 20 years, and for a human about 100 years The basic cause of aging in these organisms (eukaryotes) lies at the level of genes. This book reviews the biology of the gene in relation to aging.This book reviews the molecular biology of the gene in relation to aging. The author presents basic information on eukaryotic genes and follows this with details of the changes that occur in their structure and function during aging. He reviews the latest studies being carried out in various laboratories, outlines the gaps and deficiencies in our present knowledge, and suggests the most profitable future areas of research.1. Introduction; 2. Phenotypic changes during ageing; 3. Chromatin; 4. Eukaryotic genes; 5. Changes in gene expression during aging; 6. Theories of aging; 7. Conclusions and future prospects; References; Index. The book is densely packed to cover most areas of cellular and molecular biology in the context of ageing, and the author must be commended for keeping the text flowing through such a catalogue of information and for keeping the information correct. The Lancet ...a welcome addition to the bookshelf of the researcher on aging.... S. Michal Jazwinski, Experimental Gerontology [Kanungo] draws upon a lifetime of voracious reading to present his interpretations and suggestions for future research. Richard A. Lockshin, BioScience For those involved in research on the aging process, this is probably essential--a benchmark book. Michael JlC'