Handbook of Platelet Physiology and Pharmacology [Paperback]

This is the first comprehensive work to review blood platelet biochemistry, physiology, pharmacology, and function. It provides up-to-date information on how platelets function, the biochemical mechanisms that modulate their physiology and function, as well as the pharmacology of platelet inhibitory drugs.

Handbook of Platelet Physiology and Pharmacology represents the first comprehensive work to review blood platelet biochemistry, physiology, pharmacology and function. This edited volume provides up-to-date information on how platelets function, the biochemical mechanisms that modulate their physiology and function, as well as the pharmacology of platelet inhibitory drugs. The book presents an excellent overview of biochemistry, receptor biology, signaling mechanisms, calcium homeostasis, molecular pathology, and comparative physiology of platelets, as well as the pharmacology of antiplatelet drugs and clinical trials.
Handbook of Platelet Physiology and Pharmacology will prove a useful reference for hematologists, cell biologists, biochemists, pathologists, and other researchers in the areas of cell biology, pathobiology, atherosclerosis, thrombosis, and biomedical engineering.Contributors. Preface. Introduction. 1. Platelet Physiology & Pharmacology: An overview; G.H.R. Rao. Receptor Biology. 2. Human Platelet Thrombin Receptors and the two Receptor Model for Platelet Activation; G.A. Jamieson, et al. 3. Platelet Thromboxane Receptors: Biology and Function; G.J. Johnson. 4. Collagen Receptors: Biology and Functions; B. Kehrel. 5. Adenosine Receptors: Biology and Function; K.C. Agarwal. 6. Platelet Activating Factor and Platelets; S.D. Shukla. 7. Platelet Glycoprotein 1b-V-1X: Biology and Function; K.J. Clemetson. 8. Fibrinogen Receptors: Biology and Function; E.I. Peerschke. Platelet Biochemistry. 9. Biochemistry of Platelet Activation; A. Ryningen, H. Holmsen. 1lÓ{