A Handbook of Transcription Factors [Paperback]

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes.? In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution.?

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Written from a genome-based perspective, this volume provides an objective overview of transcription factor biochemistry. Topics include known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin.

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes.? In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution.?

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Preface; 1 Introduction to A Handbook of Transcription Factors, Timothy R. Hughes; 2 An Index of Prokaryotic Transcription Factors, Karthikeyan Sivaraman et al.; 3 A Catalogue of Eukalcö