Histological Typing of Salivary Gland Tumours [Paperback]

This second edition is more extensive and detailed than the previous one - now a reference of two decades standing. New technical methods have increased our understanding of many tumours, and the earlier group of monomorphic adenomas has been separated for easier identification, while clearly defined tumours - even if uncommon - have their own category. With reference to their differences in prognosis and treatment, the various types of carcinomas are now listed separately, and new entities have been adopted. The inclusion of the TNM classification of salivary gland tumours together with the more detailed description of the tumour-like lesions will contribute to an even better understanding.Knowledge of tumours of the salivary glands has advanced consider? ably in the two decades that have elapsed since work was started on the first edition of Histological Typing of Salivary Gland Tumours. A great deal of information has been collected about newly de? scribed tumour entities and the behaviour and prognosis of the pre? viously classified tumours. Immunohistochemistry, cytophotometry, hybridization techniques, tissue culture and chromosomal analysis have increased our understanding of many tumours. Histological Typing Histological typing divides tumours of a given organ into different types according to their direction of differentiation. Although this may frequently indicate the underlying histogenesis of the tumour, it may be difficult or impossible to identify the cell of origin. Note is taken of the structure and function of cell types, as well as the overall growth pattern of the tumour, with the aim of matching these fea? tures to those of a normal tissue found in the same organ. The principles of the second edition of the WHO Histological Typing of Salivary Gland Tumours are based on the following axioms: - The classification is orientated to the routine work of the surgical pathologist. The inclusion of rare but clearly defined tumour en? tities should be helpl(