Human T-Lymphotropic Viruses Methods and Protocols [Hardcover]

While HIV-1 continues to be well-researched, this detailed volume draws attention to other members of the Retrovirus family, namely the Human T-lymphotropic Viruses (HTLVs), featuring the most updated technical information about HTLV determination and the methods to investigate their interaction with the host immune system and interfering pathogens. The contents include essential aspects of epidemiology and virus transmission, novel and robust methodologies for studying the effects of trans-activating regulatory HTLVs proteins, the latest techniques for genotyping and gene expression analysis, as well as cellular phenotype and dynamics.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Part I: Epidemiology and Transmission

1. Serological and Molecular Methods to Study Epidemiological Aspects of Human T-Cell Lymphotropic Virus Type 1 Infection

            Olivier Cassar and Antoine Gessain

2. Molecular Epidemiology Database for Sequence Management and Data Mining

            Thessika Hiala Almeida Ara?jo, Filipe Ferreira de Almeida Rego, and Luiz Carlos Junior Alcantara

3. Reportló,