Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complexVolume I: Development of the Antibody Repertoire T Cell Antigen Receptors A Primer on Antigen Processing and Presentation The T Cell Circuits - Their Defects in Autoimmunity Hormones, Genes, and Autoimmunity Regulatory Idiotypes: Roles in Autoregulation and Autoimmunity Natural Autoantibodies in Regulation of Immune Homeostasis and Autoimmune Diseases T Cell Receptor and Autoimmune Disease Virus-Induced Autoimmunity MHC Molecule Expression in Nonlymphoid Tissue: Implication for Autoimmunity Experimental Regulation of Autoimmune kDisease Major Histocompatibility Complex Allele-Disease Associations in the Light of Extended Haplotypes Theoretical Modeling and Population Epidemiology of Complex Genetic Diseases Index