Immunotherapy and Biomarkers in Neurodegenerative Disorders [Hardcover]

This practical volume examines a number of topicsthat explore the current status of immunotherapy and diagnostic markers forneurodegenerative disorders. With a focus on Alzheimers disease, the firstsections of the book examine immunotherapeutic approaches for theaforementioned disease as well as for Parkinsons disease and Huntingtons disease,amongst others. The last section of the book covers the importance of biomarkertechniques to catch these diseases early enough for the treatments to be mostuseful. Written for the Methods inPharmacology and Toxicology series, this book contains the kind of detaileddescriptions and implementation advice that will offer a smooth transition intothe lab.

Authoritative and useful, Immunotherapy and Biomarkers inNeurodegenerative Disorders aims to aid in the continued progress in thedevelopment of novel immune-based drugs and diagnostic tools for thesedevastating brain diseases.

Part I: ImmunotherapyAgainst Amyloid-b inAlzheimers Disease

 

1. Immunotherapy Against Amyloid-? in Alzheimers Disease: An Overview

            Niels D. Prins

 

2. Active Immunization Against theAmyloid-? Peptide

            Enchi Liuand J. Michael Ryan

 

3. ImmunotherapyAgainst N-Truncated Amyloid-? Oligomers

            Thomas A.Bayer and Oliver Wirths