Inflammation and Oxidative Stress in Neurological Disorders: Effect of Lifestyle, Genes, and Age [Hardcover]

Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases?is sure to?increase?dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders?is?of critical?important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age?is intended to?facilitate and promote new discoveries for the treatment of age-related neurological disorders.

1. The effects of diet, exercise, and sleep on brain metabolism and function.-2. Biochemical Aspects of Neuroinflammation.- 3.Contribution of dietary fat in neuroinflammation.- 4. Contribution of receptors, transcription factors, and genes in the induction of neuroinflammation.- 5. Effect of exercise on neurodegeneration in neurological disorders.- 6. Neurochemical Aspects of Oxidative and Nitrosative Stress.- 7. Contribution of dietary fat in the induction of oxidative stress.- 8. Contribution of dietary carbohydrates in induction of oxidative stress.- 9. Contribution of transcription factors and genes in the induction of oxidative stress.- 10. Effect of exercise on oxidative stress in neurological disorders.- 11. Summary, perspective, and directions for future studies.

Consumption of healthy balanced diet (colored and green vegetables, fresh fruits, lean meats, fish, and whole grain) along with moderate exercise (30-45 min/day), and 6-7 hours of sleep results in a healthier blood pressure pattern and low cholesterol levels leading into a reduced risk of obesity related diseases, such as diabetes, and metabolic syndrome. Both these pathological conditions are not only the risk factors for heart disease, l£É