Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products [Hardcover]

An in-depth look at cutting-edge research on the body's innate immune system

Innate immunity is the body's first line of protection against potential microbial, viral, and environmental attacks, and the skin and oral mucosa are two of the most powerful barriers that which we rely on to stay well. The definitive book on the subject, Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products provides a comprehensive overview of these systems, including coverage of antimicrobial peptides and lipids and microbial challenges and stressors that can influence innate immunity.

Designed to help experts and newcomers alike in fields like dermatology, oral pathology, cosmetics, personal care, and pharmaceuticals, the book is filled with suggestions to assist research and development. Looking at the many challenges facing the innate immune system, including the impact of topically applied skin products and medications, Innate Immune System of Skin and Oral Mucosa paves the way for next generation treatment avenues, preventative approaches, and drug development.

Contributors xi

Part I Overview of Skin and Muscosal Innate Immunity: History, Ethics, and Science

Chapter 1 Germ Free: Hygiene History and Consuming Antimicrobial and Antiseptic Products 3
Jennifer Tebbe-Grossman and Martha N. Gardner

Chapter 2 Ethical Responsibilities in Formulating, Marketing, and Using Antimicrobial Personal Products 43
Kenneth A. Richman

Chapter 3 Role of Stratum Corneum in Permeability Barrier Function and Antimicrobial Defense 59
Peter M. Elias

Part II Antimicrobial Lipids and Peptides

Chapter 4 Antimicrobial Lipids ofl³-