Ion Channels Molecules in Action [Paperback]

Up-to-date introduction to ion channels and how they work, emphasising their molecular structure.Ion channels are crucial components of living cells. This overview of ion channel study includes up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction.Ion channels are crucial components of living cells. This overview of ion channel study includes up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction.Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.Preface; 1. Introduction; 2. Ions on the move; 3. Investigating channel activity; 4. Molecular structures; 5. Permeability and selectivity; 6. Gating and modulation; 7. Drugs and toxins; 8. Dysfunctional channels in human disease; 9. Not the last word; References; Index. ...[a] clear and concise introduction to the physics, chemistry, and molecular biology used for ion channel research...what distinguishes this book from standard textbooks is the inclusion of some details of the experimental design, so as to allow the reader to have a better feel of how the studies were done and how the abstract theories emerged from the data...The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas. Lily Yeh Jan, Cell ...this book takes the reader l,