The median age of survival for those with cystic fibrosis has risen considerably in recent years. This text thoroughly examines the developments and breakthroughs which have led to this improvement in life expectancy. With a focus on the latest discoveries in the diagnosis and treatment of the disease, this book provides a comprehensive overview of the past, current and forthcoming advancements in cystic fibrosis research and clinical care.
Preface
Contributors
Pathophysiology
The Genetics of Cystic Fibrosis Laurence Suaud and Ronald C. Rubenstein
Ion Transport James L. Kreindler and J. Kevin Foskett
Mucus Abnormalities and Ciliary Dysfunction A. Whitney Brown and Scott H. Donaldson
Microbiology in Cystic Fibrosis Paul J. Planet and Lisa Saiman
Inflammation in the Cystic Fibrosis Lung James F. Chmiel and Michael W. Konstan
Modifier Genes of Cystic Fibrosis Mitchell Drumm
Diagnostics
Cystic Fibrosis: Diagnosis, Sweat Testing, and Newborn Screening Brian P. OSullivan
Diagnostic Approach to Diseases Associated with Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations Chee Y. Ooi (Keith), Elizabeth Tullis, and Peter R. Durie
Lung Function Testing in Infants Jessica E. Pittman and Stephanie D. Davis
Assessment of Lung Function in Young Children with Cystic Fibrosis Fariba Rezaee and Clement L. Ren
Lung Function Testing in School-Age Children with Cystic Fibrosis Oscar H. Mayer and Julian L. Allen
Thoracic Imaging in Cystic Fibrosis Pulmonary Disease Molly Raske and Alan S. Brody
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