When the first edition ofPediatric Psychopharmacologypublished in 2002, it filled a void in child and adolescent psychiatry and quickly establishing itself as the definitive text-reference in pediatric psychopharmacology. While numerous short, clinically focused paperbacks have been published since then, no competitors with the scholarly breadth, depth, and luster of this volume have emerged. In the second edition, Christopher Kratochvil, MD, a highly respected expert in pediatric psychopharmacology, joins the outstanding editorial team led by Dr. Martin and Dr. Scahill. In the new edition, the editors streamline the flow of information to reflect the growth in scientific data since the first edition appeared. The overall structure of the book remains the same, with major sections on underlying biology; somatic interventions; assessment and treatment; and special considerations.
Final Table of Contents:
Contributors xxi SECTION I BIOLOGICAL BASES OF PEDIATRIC PSYCHOPHARMACOLOGY I-A Developmental Principles of Neurobiology and Psychopharmacology 3 1. Overview of Brain Development 5 Flora M. Vaccarino and James F. Leckman 2. Synaptic Function and Biochemical Neuroanatomy 23 Stephan Heckers, Christine Konradi, and George M. Anderson 3. Developmental Principles of Pharmacokinetics 38 Alexander A. Vinks, Philip D. Walson, and Shannon N. Salda?a 4. Cytochrome P450-Mediated Interactions 50 Jessica Oesterheld and Miia Turpeinen I-B Genetic Principles 65 5. Molecular Genetics 67 Susan Goebel-Goody, Surojit Paul, and Paul J. Lombroso 6. Pharmacogenetics 81 George M. Anderson, Jeremy Veenstra-VanderWeele, Edwin H. Cook, and James T. McCracken I-C Developmental Psychopathology 93 7. Neurobiology of Attention Regulation and its Disorders 95 A.F.T. Arnsten and F.X. Castellanos 8. Neurobiology of Early Life Stress: Evolving Concepts 112 Joan Kaufman and Natalie Weder 9. Neurobiology of Earll%