Focus on Extrapyramidal Dysfunction [Paperback]

Experts in the fields of neurology, neuroscience, neurobiology and psychiatry review and present novel findings of basic and clinical research on extrapyramidal disorders and allied conditions. New insights on the nature of extrapyramidal dysfunction and its therapy in the fields of neurology, psychiatry and neuroscience are presented.Dopaminergic neurotoxicity of homocysteine and its derivatives in primary mesencephalic cultures.- MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinsons disease.- Screening for mutations in synaptotagmin XI in Parkinsons disease.- Depletion and restoration of endogenous monoamines affects ?-CIT binding to serotonin but not dopamine transporters in non-human primates.- Differential executive control impairments in early Parkinsons disease.- Simple movement sequences better correlate to levodopa plasma levels than complex ones.- Clinical effects of repetitive transcranial magnetic stimulation versus acute levodopa challenge.- Impact of apomorphine on BOLD signal during movement in normals.- Worsened motor test performance following acute apomorphine injection in previously untreated patients with Parkinsons disease.- Transdermal lisuride delivery in the treatment of Parkinsons disease.- Congruent deterioration of complex and simple movements in patients with Huntingtons disease.- Methyltetrahydrofolate reductase polymorphism influences onset of Huntingtons disease.- Coenzyme Q10 serum levels in Huntingtons disease.- The N-methyl-D-aspartate antagonist memantine retards progression of Huntingtons disease.- Transcranial sonography in spinocerebellar ataxia type 3.- Therapeutic strategies in Friedreichs ataxia.- Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder.comprehensive presentation of basic and clinical research on extrapyramidal dysfunction new therapeutic principles in extrapyramidal disorders novel findings in Parkinsons disease, lc/