The book will discuss classes of proteins and their folding, as well as the involvement of bioinformatics in solving the protein folding problem. In vivo and in vitro folding mechanisms are examined, as well as the failures of in vitro folding, a mechanism helpful in understanding disease caused by misfolding.?The role of energy landscapes is also discussed and the computational approaches to these landscapes.Research Updates on Protein Folding.- Classes of Protein and their Folding.- Energetics of Protein Folding and Significance of Intermediates.- Involvement of Bioinformatics in Solving Protein Folding Problem.Discusses major problems in protein folding Provides up-to-date research topics addressing protein folding challenges Discusses the use of bioinformatics in solving protein folding challenges Includes supplementary material: sn.pub/extras