Regio- and Stereo-Controlled Oxidations and Reductions [Hardcover]

Volume 5 in the Catalysts for Fine Chemical Synthesis series describes new procedures for the regio- and stereo-controlled transformations of compounds involving oxidation or reduction reactions. It describes a wide range of catalysts, including organometallic systems, biocatalysts and biomimetics. This volume also includes descriptions of a variety of conversions, including: Baeyer-Villiger oxidations; Epoxidation reactions; Hydroxylation reactions; Oxidation of alcohols to aldehydes, ketones and carboxylic acids; Reduction of ketones; and Reduction of alkenes including α, β-unsaturated carbonyl compounds. The book will be an important text for practising synthetic organic chemists in industry and academia.

• Protocols are written in a standard format by the authors who have discovered them
• Hints, tips and safety advice (where appropriate) is given to ensure that the procedures are reproducible
• Indications are given as to the range of starting materials used and, where appropriate, comparisons to alternative methodology
• Includes relevant references to the primary literature.

CHAPTER 1: Industrial Catalysts for Regio- or Stereo- selective Oxidations and Reductions. A Review of Key Technologies and Targets.
J. Whittall

CHAPTER 2: Asymmetric Hydrogenation of Alkenes, Enones, Ene-esters and Ene-Acids

2.1: (S)-2,2'- Bis{[di(4-methoxyphenyl)phosphinyl]oxy}-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl as a Ligand for Rhodium-Catalysed Asymmetric Hydrogenation
I. Gergely, C. Hegeds and J. Bakos.

2.2: Synthesis and Application of Phosphinite Oxazoline Iridium Complexes for the Asymmetric Hydrogenation of Alkenes
F. Menges and A. Pfaltz.

2.3: Synthesis and Application of Heterocyclic Phosphine Oxazoline (HetPHOX) IrlÆ