Revival: Glutathione (1990) [Paperback]

This important book is to present the reader with developments concerning glutathione research. This work focuses on the synthesis-degradation and oxidation-reduction cycles of glutathione, the physiological functions of glutathione (especially in mammalian cells), and the analytical methods used to accurately measure the glutathione status of cells. This resource addresses specific modification of glutathione metabolism that is of special interest in the treatment of some tumors. This rare volume also introduces some different, new techniques on how to accurately measure glutathione, specifically in its oxidized form. Anyone involved with biochemistry, physiology, toxicology, pharmacology, nutrition and radiation biology will find this publication interesting and filled with useful information. It is also a valuable reference for research scientists in such fields as aging, metabolism disorders, and glutathione research.1. Publications on Glutathione, 1983-1987, A Bibliometric Study  2. Determination of Tissue Glutathione  3. Manipulation of Liver Glutathione Status-A Double-Edged Sword  4. Compartmentation of Cellular Glutathione in Mitochondrial and Cytosolic Pools  5. Hormonal Influence of GSH Content in Isolated Hepatocytes  6. Glutathione Transport and Its Significance in Oxidative Stress  7. Glutathione and Alcohol. Glutathione in Prokaryotes  8. Biosynthesis and Regulation of g-Glutamyl Transpeptidase  9. The Role of g-Glutamyl Transpeptidase (g GTPase) in Mammary Tissue  10. Structure, Mechanism, Functions, and Regulatory Properties of Glutathione Reductase  11. Glutathione Transferase in Human Tumors and Human Cancer Cell Lines  12. The Formation of Disulphide Bonds in the Synthesis of Secretory Proteins: Properties and Role of Protein Disulfide-Isomerase  13. The Glyoxalase System: Towards Functional Characterization and a Role in Disease Plã*