Clinical Trials In Parkinson's Disease [Hardcover]

This volume looks at major clinical trials for motor and non-motor symptoms in Parkinsons Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center.

Cutting-edge and authoritative, Clinical Trials in Parkinsons Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials.   

Toxin-Based Rodent Models of Parkinsons Disease.- Assessment of Non-Motor Symptoms in Rodent Models of Parkinsons Disease.- Genetic Models of Parkinsons Disease.- A Review of Randomized Phase III Pharmacological Clinical Trials for Motor Symptoms in Parkinsons Disease Patients and Quality of Evidence Recommendations.- Clinical Trials for Motor Complications in Parkinsons Disease.- Clinical Trials for Gait Disorders in Parkinsons Disease.- Clinical Trials for Disease Modifying Agents in Parkinsons Disease.- Value and Methods of Pharmacovigilance in the Monitoring of Drug Safety in Parkinsons Disease.- Clinical Trials for Cognitive Impairment and Dementia in Parkinsons Disease.- Clinical Trials for Depression, Anxiety, Fatigue, and Apathy in Parkinsons Disease.- Clinical Trials for l+