Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications [Hardcover]

I Lipdxygenases and Leukotriene Biosynthesis.- 1. Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases.- 2. 5-Lipoxygenase and the Nucleus: Where, When, How, and Why?.- 3. Calcium Binding Site of 5-Lipoxygenase.- 4. Regulation of Cellular 5-Lipoxygenase Activity by Glutathione Peroxidases.- 5. Novel Aspects Related to Biosynthesis and Biological Actions of Hepoxilins: Interrelationship with Phospholipid Hydro-Peroxide Glutathione Peroxidase (PHGPx).- 6. Transcriptional Regulation of the Human Leukotriene C4 Synthase Promoter.- 7. Localization and Translocation of Enzymes Involved in Leukotriene Biosynthesis.- II Cyclooxygenases and Prostaglandin Biosynthesis.- 8. Regulation of COX-2 Expression in Fibroblasts, Osteoblasts, Mast Cells, and Macrophages.- 9. Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions.- 10. Substrate Interactions in the Cyclooxygenase-1 Active Site.- 11. Mutation of the Human Prostacyclin Synthase Gene.- 12. Structure and Function of Two Distinct Types of Prostaglandin D Synthase.- 13. Roles of Prostaglandin F Synthase.- 14. Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells.- III Phospholipase A2.- 15. On the Functional Diversity of Secreted Phospholipases A2: Cloning of Novel Mammalian and HIV-1 Antiviral Properties.- 16. Regulation of Cytosolic Phospholipase A2 by Phosphorylation.- IV Cytochrome P450 Archidonate Metabolites.- 17. Synthesis and Function of 20-Hydroxyeicosatetraenoic Acid in the Kidney.- V Receptors.- 18. Altered Bronchodilation and Pulmonary Inflammation in Prostanoid EP2 Receptor Knockout Mice.- 19. Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell.- 20. BLT2, aSecond Leukotriene B4 Receptor.- 21. Upregulation of Cysteinyl-Leukotriene 1 Receptor Expression by Interleukin-5 in Human Leukocytes.- 22. Physiological and Pathophysiological Roles of Prostanoids; Lel£J