Side-Effects of Anti-Inflammatory Drugs: Part Two Studies in Major Organ Systems [Paperback]

2 Table of Contents.- Section III Gastrointestinal Tract (Experimental Aspects).- 1 Mechanisms of gastric contrasted with intestinal damage by non-steroidal anti-inflammatory drugs.- Discussion.- 2 The enterohepatic circulation of some anti-inflammatory drugs may cause intestinal ulcerations.- Discussion.- 3 Limitations of laboratory models in predicting gastrointestinal toleration of oxicams and other anti-inflammatory drugs.- 4 Why are non-steroidal anti-inflammatory drugs so gastrotoxic, even when given orally as solubilized salt formulations or parenterally?.- 5 Early and late phases in the formation by anti-inflammatory drugs of intestinal lesions in rats.- 6 Role of intestinal microflora in maintaining indomethacin induced intestinal lesions in rats.- 7 Comparison of gastric mucosal damage and prostaglandin formation in arthritis patients treated with carprofen and ibuprofen.- 8 Inhibition of prostanoid synthesis by anti-inflammatory drugs in human gastric mucosa.- 9 Leukotriene formation in the gastrointestinal tract and effects of anti-inflammatory drugs.- 10 Evidence for sulphydryl-sensitive process in the mechanisms of acute gastric mucosal injury and defence.- 11 Experimental and clinical studies on the prevention of aspirin-induced gastric damage by cytoprotective drugs.- 12 Both E prostaglandins and prolonged indomethacin treatment exert trophic effects on the gastric mucosa.- 13 Gastrointestinal side-effects of prostaglandins.- 14 Investigation of auranofin-induced diarrhoea.- 15 Pyrido-pyrimidines  with analgesic and anti-inflammatory activity  inhibit the gastrointestinal mucosal damage induced by different prostaglandin synthesis inhibitors.- 16 Al(OH)3 inhibits aspirin-induced gastric lesions in cats with Heidenhain pouch.- 17 Polyenephosphatidylcholine: an inhibitor of NSAID gastric toxicity which increases impaired mucosal PGE2 synthesis.- 18 Prostaglandins prevent red streaks in rat gastric mucosa caused by intravenous aspirin but not by sall“$