Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective [Hardcover]

From the introduction: The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 years on the physiology of intraocular pressure, ocular blood flow and the relation of these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the authors own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby led to new methods of diagnosis and therapy.

Invasive Studies of the Parameters Regulating Ocular Physiology and Vision.- In Vivo Manometric Studies of the Steady State Intraocular Pressure and the Intraocular Pressure Pulse in Animals and Man.- The Rate of Formation of the Aqueous Humor.- The Steady State Intraocular Pressure/Flow Relations in Dead and Living Animal and Human Eyes.- Homeostasis, Autoregulation, and Relative Ischemia.- The Pressure/Volume Relation in Eyes of Dead and Living Animal and Human Eyes.- The Ocular Perfusion Pressure and Its Influence on the Intraocular Pressure Pulse.- Direct and Indirect Measurements of Ocular Blood Flow in Anesthetized and Conscious Animals and Humans.- The Morphology and Hydrodynamics of the Chamber Angle Draining the Aqueous Humor.- The Sympathetic Nerve Innervation of the Eye and the Actions of the Adrenergic Neuron Transmitter Norepinephrine on Intraocular Pressure and Ocular Blood Flow.- Manometric Studies ?on the Intraocular Pressure and Vascular Circulation in Ophthalmic Disease.- Noninvasive Studies on the IOP, PA, and Blood Flow Autoregulation in Healthy and Diseased Eyes.- Indirect Measurements of the Intraocular Pressure and thl&