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The management of a patient with cerebral venous sinus thrombosis.This Element covers the common presentations and epidemiology of cerebral venous sinus thrombosis, progressing through the approach to investigation and management of this condition in the acute, sub-acute and more chronic timeframes.This Element covers the common presentations and epidemiology of cerebral venous sinus thrombosis, progressing through the approach to investigation and management of this condition in the acute, sub-acute and more chronic timeframes.Cerebral venous sinus thrombosis (CVST) is a serious and potentially life-threatening condition, whose diagnosis is often missed or delayed due to often non-specific presentations. However, if diagnosed and managed appropriately prognosis is generally favourable. This Element covers the common presentations and epidemiology of CVST, progressing through the approach to investigation and management of this condition in the acute, sub-acute and more chronic timeframes.Epidemiology; Clinical presentation; Use of appropriate investigation; Management of CVST; Complications and prognosis; Clinical vignette.