A Holistic Approach to Organic Synthesis [Hardcover]

Synthesis is one of the distinguishing features of chemistry as a science. It is the synthetic chemist who uses their intimate understanding of molecular structure and properties to produce materials of great value to society.

Chapter 1 A Simple Holistic Approach to Planning a Synthesis

Chapter 2 Vying for Control: The Synthesis of Reserpine and Quinine

Chapter 3 A Helping Hand from Nature? Bioinspired Synthesis and Semi-synthesis

Chapter 4 Prostaglandins and Triquinanes: Fertile Ground for Method Development

Chapter 5 Polyketide Synthesis: The Challenge of Acyclic Stereocontrol

Synthesis is one of the distinguishing features of chemistry as a science. It is the synthetic chemist who uses their intimate understanding of molecular structure and properties to produce materials of great value to society. Thus, it is important for students of chemistry to study synthesis and acquire a working knowledge that enables them to address the following question: given a specific molecular target, how does one formulate a plan for its synthesis? This synthesis primer provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis. It may be used in conjunction with a synthetic methods course, or it can stand alone.

Features:

• Provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis
• Serves to help organic chemists at all levels to better understand published syntheses
• Focuses on natural products, their complexity, and diverse structures which challenge and inspire the chemists preparing them