Practical Bioinformatics?is designed as an introduction to bioinformatics sequence analysis. It contains many exercises such as database searches, protein analysis, and data interpretation to complement the straightforward and practical topics. The chapters are focused on DNA, RNA, and protein sequence analysis.
1. Introduction to Bioinformatics and Sequence Analysis
2. Introduction to Internet Resources
3. Introduction to the BLAST Suite and BLASTN
4. Protein BLAST: BLASTP
5. Cross-Molecular Searches: BLASTX and TBLASTN
6. Advanced Topics in BLAST
7. Bioinformatics Tools for the Laboratory
8. Protein Analysis
9. Explorations of Short Nucleotide Sequences
10. MicroRNAs
11. Multiple Sequence Alignments
12. Browsing the Genome
Appendix: Formatting Your Report
Abbreviations
Glossary
Web Resources
Michael Agostino received his PhD in molecular biology from Roswell Park, a division of SUNY at Buffalo, New York. He did genetic engineering laboratory research for 13 years before making the formal switch to bioinformatics, working at GlaxoSmithKline, Genetics Institute, and Pfizer for over 33 years. At those companies he worked with other scientists, providing sequence analysis support for projects too numerous to count. Michael is now an instructor for Harvard Extension School, where, for 10 years, he has been teaching a course largely based on this book.
Practical Bioinformatics is specifically designed as an introduction to bioinformatics sequence analysis. Many readers are exploring their future paths or are fascinated by the headlines about interesting gene discoveries and want to understand more. There is heavy emphasis on the steps required to perform bioinformatics analysis to answer biological questions. The bool#u