Mass Spectrometry for the Analysis of Pesticide Residues and their Metabolites [Hardcover]

• Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment
• Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications
• Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in combination with MS for the analysis of pesticides
• Describes various established and new ionization techniques as well as the main MS platforms, software tools and mass spectral libraries

List of contributors xi

Foreword xiii

Preface xv

1 Pesticide Chemistry and Risk Assessment 1
Despina Tsipi, Helen Botitsi, and Anastasios Economou

1.1 Introduction 1

1.2 Pesticide Chemistry 2

1.2.1 Historical Perspective 2

1.2.2 Identity and Physicochemical Properties of Pesticides 2

1.2.3 Pesticide Classification 4

1.2.4 Modes of Action (MoA) 5

1.3 Pesticide Metabolites and Transformation Products 8

1.3.1 Biotransformation 9

1.3.2 Environmental Fate 13

1.4 Risk Assessment 14

1.4.1 Safety Factors 14

1.4.2 Ecological Risk Assessment for Pesticides 15

1.5 Dietary Exposure to Pesticides 17

1.5.1 Acute Exposure or ShortTerm Intake 18

1.5.2 Chronic Exposure or LongTerm Intake 18

1.5.3 Cumulative Exposure to Multiple Substances 18