Metal Catalysed Carbon-Carbon Bond-Forming Reactions [Hardcover]

The chemist has a vast range of high-tech catalysts to use when working in fine chemical synthesis but the catalysts are generally hard to use and require both time, skill and experience to handle properly. The Catalysts for Fine Chemical Synthesis series contains tested and validated procedures which provide a unique range resources for chemists who work in organic chemistry.

... of great value to synthetic organic chemists... (The Chemists, Summer 2003)

Volume 3 in the series focuses on catalysts for carbon-carbon bond formation and presents practical  and detailed protocols on how to use sophisticated catalysts by the inventors and developers who created them. The combination of protocols and review commentaries helps the reader to easily and quickly understand and use the new high-tech catalysts.

Series Preface.

Preface to Volume 3.

Abbreviations.

List of Chemical Names Used.

1 Considerations of Industrial Fine Chemical Synthesis (Mark W. Hooper).

1.1 Introduction

1.2 Types of processes – flow charts.

1.3 Costs associated with use of catalysts.

2 Alkylation and Allylation Adjacent to a Carbonyl Group.

2.1 The RuH<sub>2</sub>(CO)(PPh<sub>3</sub>)<sub>3</sub>-catalysed alkylation, alkenylation and arylation of aromatic ketones via carbon-hydrogen bond cleavage (Fumitoshi Kakiuchi, Satoshi Ueno and Naoto Chatani).

2.2 Catalytic, asymmetric synthesis of a,a-disubstituted amino acids using a chiral copper-salen complex as a phase transfer catalyst (Michael North and Jose A. Fuentes).

2.3 Asymmetric l•