Metallomics and the Cell [Paperback]

Metallomics and the Cell provides in an authoritative and timely manner in 16 stimulating chapters, written by 37 internationally recognized experts from 9 nations, and supported by more than 3000 references, several tables, and 110 illustrations, mostly in color, a most up-to-date view of the metallomes which, as defined in the omics world, describe the entire set of biomolecules that interact with or are affected by each metal ion. The most relevant tools for visualizing metal ions in the cell and the most suitable bioinformatic tools for browsing genomes to identify metal-binding proteins are also presented. Thus, MILS-12 is of relevance for structural and systems biology, inorganic biological chemistry, genetics, medicine, diagnostics, as well as teaching, etc.

1. Metallomics: Some Definitions and General Comments by Lucia Banci and Ivano Bertini

2. Technologies for Detecting Metals in Single Cells by James E. Penner-Hahn

3. Sodium/Potassium Homeostasis in the Cell by Michael V. Clausen and Hanne Poulsen

4. Cellular Magnesium Homeostasis in Mammalian Cells by Andrea M. P. Romani

5. Intracellular Calcium Homeostasis and Signaling by Marisa Brini, Tito Cali, Denis Ottolini, and Ernesto Carafoli

6. Manganese Homeostasis and Transport by Jerome Roth, Silvia Ponzoni, and Michael Aschner

7. Control of Iron Metabolism in Bacteria by Ian Norton, Arvindkumar S. Salunkhe, Helen Goodluck, Wafaa S. M. Aly, Hanna Mourad-Agha, Pierre Cornelis^, and Simon Andrews

8. The Iron Metallome in Eukaryotic Ol“\