Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.1 Motor Neuron Disease: The Clinical Syndrome.- Classification of Motor Neuron Diseases.- Spinal Muscular Atrophies.- Motor Neuron Disease (Amyotrophic Lateral Sclerosis).- Clinical Features.- Other Clinical Syndromes of MND.- Outcome of MND.- Possible Associations of MND with Other Diseases.- Poliomyelitis.- Hexosaminidase Deficiency (GM2 Gangliosidosis).- MND and Plasma Cell Dyscrasia.- Hyperparathyroidism and Thyrotoxicosis.- AIDS.- Creutzfeldt-Jakob Disease.- Other Disorders.- Diagnosis and Investigation.- Differential Diagnosis.- 2 Epidemiology of Motor Neuron Disease.- Some Important Clinical Patterns of Motor Neuron Disease/Al#*