Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors [Paperback]

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies.

• Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness
• Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine
• Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors

1. Introduction: An Overview of the Anatomy and Physiology of the Brain
2. Angiogenesis in brain tumors
3. Physiology of the Blood Brain Barrier (BBB) and mechanisms of Transport across the BBB
4. Active Targeting Systems (Ligands) / Receptor overexpressed on brain
5. Nanotechnology in Brain Targeting
6. Polymeric nanoparticles based drug delivery for brain tumors
7. Solid lipid nanoparticles (SLN)based drug delivery for brain tumors
8. Liposomes based drug delivery for brain tumors
9. Dendrimers based drug delivery for brain tumors
10. Micelles based drug delivery for brain tumors
11. Nanoemulsions based drug delivery for brain tumors
12. Nanogel based drug delivery for brain tumors
13. Beyond the blood-brain barrier - facing new challenges
14. Towards development of neuro-diagnostic nanlƒ