Natural Killer Cells At the Forefront of Modern Immunology [Hardcover]

Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.

Natural killer (NK) cells are at the forefront of immunology. This book describes in detail current knowledge about NK cells. It covers a broad range of NK cell-related topics, including those that are not frequently reviewed.

Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.

Natural Killer Cells: Deciphering Their Role, Diversity and Functions.- Dissecting Human NK Cell Development and Differentiation.- Diversity of KIR Genes, Alleles and Haplotypes.- NK Cell Education and CIS Interaction Between Inhibitory NK Cell Receptors and Their Ligands.- Trogocytosis and NK Cells in Mouse and Man.- Virus Interactions with NK Cell Receptors.- The Role of NK Cells in Bacterial Infectilƒ