Naturally Occurring Antibodies (NAbs) [Hardcover]

This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.

Here, pioneering researchers report on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. The volume also has a chapter on the history of how pooled plasma was pretreated for safe intravenous use.

Naturally Occurring IgM Antibodies to OxidationSpecific Epitopes.- Naturally Occurring Autoantibodies to Apoptotic Cells.- Naturally Occurring Antibodies Directed against Carbohydrate Tumor Antigens.- Naturally Occurring Antibodies as Therapeutics for Neurologic Disease: Can Human Monoclonal IgMs Replace the Limited Resource IVIG?.- Nature and Nurture of Catalytic Antibodies.- Naturally Occurring Autoantibodies in Mediating Clearance of Senescent Red Blood Cells.- Naturally Occurring Autoantibodies against bAmyloid.- MultiFaceted Role of Naturally Occurring Autoantibodies in Fighting Pathogens.- Immunoregulation by Naturally Occurring and DiseaseAssociated Autoantibodies: Binding to Cytokines and their Role in Regulation of TCell Responses.- Modulation of Dendritic Cells and Regulatory T Cells by Naturally Occurring Antibodies.- Control of B Cells Expressing Naturally Occurring Autoantibodies.- Granulocyte Death Regl³2