New Frontiers in the Study of Gene Functions [Paperback]

1 The Role of Cis- and Trans-Acting Functions in Simian Virus 40 Gene Regulation.- 1. Introduction.- 2. Early Viral Transcriptional Program.- 3. Late Viral Transcriptional Program.- 4. Discussion.- References.- 2 Regulation of the Heat-Shock Response in Escherichia coli.- 1. Introduction.- 2. Transcription of the Heat-Shock Genes.- 3. Regulation of rpoH and ?32.- 4. Function of the Heat-Shock Proteins.- 5. Summary.- References.- 3 Negative Control of DNA Replication Revealed in Composite Simian Virus 40-Bovine Papillomavirus Plasmids.- 1. Overview.- 2. Introduction.- 3. Results.- 3.1. Construction of Composite Simian Virus 40-Bovine Papillomavirus Replicons.- 3.2. Construction of Permanent Cell Lines Containing Simian Virus 40-Bovine Papillomavirus Composite Plasmids.- 4. Discussion.- 4.1. Negative Control of DNA Replication.- 4.2. Mechanisms of Replication Control.- 4.3. Gene Amplification.- 4.4. Relation to the Inactive Mating-Type Cassettes in Yeast.- References.- 4 DNA Supercoiling as a Regulator of Bacterial Gene Expression.- 1. Introduction.- 2. Results and Discussion.- References.- 5 Retrotransposition in Yeast.- 1. Introduction.- 2. Experiments.- 3. Speculation.- References.- 6 Comparative Genetic Analysis of Homeobox Genes in Mouse and Man.- 1. Introduction.- 2. Murine Homeobox Genes.- 3. Human Homeobox Genes.- 4. Comparative Genetic Relationships between Species.- 5. Comparative Genetic Relationships within Species.- 6. Possible Functional Relationships between Homeobox Loci and Linked Genes.- 6.1. Mouse Hox-1, Chromosome 6.- 6.2. Mouse Hox-2, Chromosome 11.- 6.3. Mouse Hox-3, Chromosome 15.- 6.4. Human Hox-1, Chromosome 7.- 6.5. Human Hox-2, Chromosome 17.- 7. Discussion.- References.- 7 Eukaryotic Transcriptional Specificity Conferred by DNA-Binding Proteins.- 1. Introduction.- 2. Results and Discussion.- 2.1. Cis and Trans Regulatory Components of the Simian Virus 40 Promoter.- 2.2. Role of Sp1 in Other Viral and Cellular Promoters.- 2.3. A Consensus Spl£#