Ocular Pharmacology and Toxicology [Hardcover]

Covering ocular pharmacokinetics, pharmacodynamics, and toxicology, Ocular Pharmacology and Toxicology provides ophthalmologists, toxicologists, and pharmacologists with both an introduction to the proper methods for ocular pharmacology and toxicology as well as providing practical methodologies for conducting ocular studies.?Expert authors have contributed detailed chapters on study design, analysis, and routes to regulatory approval for various types and routes of ophthalmic drugs.?As a volume in the Methods in Pharmacology and Toxicology series, chapters feature the kind of in-depth specifics and implementation advice to ensure successful results.

Practical and authoritative, Ocular Pharmacology and Toxicology serves as an ideal basis of training in the proper design and conduct of essential studies to accurately determine pharmacokinetics and ocular toxicity from the systemic, topical, periocular, or intraocular administration of drugs or compounds, from the use of ocular medical devices and from ocular surgical procedures.

1. Challenges in Ocular Pharmacokinetics, Pharmacodynamics, and Toxicology

??????????? Brian C. Gilger

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2. Selection of Appropriate Animal Models in Ocular Research: Ocular Anatomy and Physiology of Common Animal Models

??????????? Brian C. Gilger, Eva Abarca, and Jacklyn H. Salmon

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3. Challenges and Strategies in Drug Residue Measurement (Bioanalysis) of Ocular Tissues

??????????? Poonam R Velagaleti and Michael H. Buonarati

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4. Chemistry, Manufacturing, and Control of Ophthalmic Formulations

??????????? Malay Ghosh and Imran Ahmed

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5. ADME and Ocular Therapeutics: Retina

??????????? Cornelis J. Van der Schyls�