Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition [Hardcover]

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed.

This is a revised edition of a very successful book, which appeals to both academic and industrial markets.

• Illustrates the organic mechanism associated with each enzyme-catalyzed reaction
• Makes the connection between organic reaction mechanisms and enzyme mechanisms
• Compiles the latest information about molecular mechanisms of enzyme reactions
• Accompanied by clearly drawn structures, schemes, and figures
• Includes an extensive bibliography on enzyme mechanisms covering the last 30 years
• Explains how enzymes can accelerate the rates of chemical reactions with high specificity
• Provides approaches to the design of inhibitors of enzyme-catalyzed reactions
• Categorizes the cofactors that are appropriate for catalyzing different classes of reactions
• Shows how chemical enzyme models are used for mechanistic studies
• Describes catalytic antibody design and mechanism
• Includes problem sets and solutions for each chapter
• Written in an informal and didactic style

Enzymes as Catalysts
Group Transfer Reactions: Hydrolysis, Amination, Phosphorylation
Reduction and Oxidation
Monooxygenation
Dioxygenation
Substitutions
Carboxylations
Decarboxylation
Isomerizations
Eliminations and Additions
Aldol and Claisen Reactions and Retroreactions
Formylations, ló~