This volume reviews the state-of-the-art in osteoarthritis. The pathogenetic roles of mechanical, systemic and inflammatory factors and the importance of neurogenic factors in pain management and in the causes of disease are considered. Of particular value is the review of the implications of pathogenetic mechanisms in future modes of management. The concept of activated arthrosis is given special attention. Finally, controversial issues and new areas for investigation are discussed. The book will help the clinician and the investigator consider the importance of addressing different phases and subtypes of osteoarthritis in planning treatment.Welcome Address.- Osteoarthrosis (Osteoarthritis) Opening Remarks.- Osteoarthritis: State of the Art.- Interaction Between Cartilage Metabolism and Inflammation.- Basic Mechanisms of Pain and Pain Therapy Related to Osteoarthritis and Other Disorders of the Musculoskeletal System.- Course of Degenerative Joint Diseases.- Therapeutic Interventions in the Treatment of Acute and Chronic Pain in Osteoarthrosis.- Round-Table Discussion.- Concluding Remarks.Springer Book ArchivesGPSR ComplianceThe European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this.If you have any concerns about our products you can contact us on ProductSafety@springernature.com.In case Publisher is established outside the EU, the EU authorized representative is:Springer Nature Customer Service Center GmbHEuropaplatz 369115 Heidelberg, GermanyProductSafety@springernature.com