Particle-Lung Interactions, Second Edition [Hardcover]

Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.

Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.

Introduction Preface Part 1: Structure and Function of the Lung 1. Functional Aspects of Lung Structure as Related to Interaction with Particles Part 2: Particle Characteristics2. Ambient Tropospheric Particles 3. Manufactured Nanoparticles 4. Particulate Carriers for Pulmonary Drug Delivery Part 3: Inhalation of Particles 5. Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Sized Particles in the Respiratory Tract Part 4: Health Effects of Particle Inhalation6. The Epidemiology of Particle Health Effects 7. Cardiovascular Consequences of Particles 8. Autonomic Mediation of the Cardiac Responses to Particle Exposure 9. Effects of Airborne Particles on Respiratory Viral Infection 10. Airborne Particles and Structural Remodeling of the Lungs Part 5: Cellular and Molecular Mechanisms of Particle Health Effects 11. Effect of Particles on Mucus and Mucociliary Clearance 12. The Role of Surfactant in Particle Exposure 13. NanoparticleCell Membrane Interactions 14. Mechanisms and Processes Underlying Toxicological Responses to Pl“A