Pathophysiology and Pharmacology of Erythropoietin [Paperback]

List of Contents.- I. Structure and Action.- Structure-Function Relationships of Erythropoietin.- Isoforms of Recombinant Human Erythropoietin.- Activation of the Erythropoietin Receptor in the T3C12 Friend Erythroleukemia Cell Line.- II. Sites and Control of Production.- The Role of Adenosine in Hypoxic Regulation of Kidney Production of Erythropoietin.- Oxygen Shunt Diffusion in Renal Cortex and Its Physiological Link to Erythropoietin Production.- Oxygen Sensing and Erythropoietin mRNA Production in Isolated Perfused Rat Kidneys.- Analysis of Erythropoietin Gene Expression by Means of Competitive Polymerase Chain Reaction.- The Developmental Biology of Erythropoiesis and Erythropoietin: Is Erythropoietin a True Hormone or a Paracrine Factor.- Insulin-like Growth Factor 1 and Erythropoiesis During Growth.- III. Blood Levels in Health and Disease.- Clinical Applicability of the Determination of Erythropoietin.- A Sensitive ELISA for Erythropoietin and Its Application in Various Diseases.- Use of Erythropoietin Radioimmunoassay in Polycythemias.- Effects of Exercise on Plasma Erythropoietin in Natives Living Permanently at High Altitude.- Erythropoietin Concentration in Renal Venous Blood in Patient with Renovascular Hypertension: Is It a Marker of Renal Ischemia.- Serum Erythropoietin Levels in Von Hippel-Lindau Syndrome.- IV. Erythropoietin Replacement in Renal Failure.- Iron Metabolism Under Treatment of Renal Anemia with Recombinant Human Erythropoietin.- Erythropoietin Treatment in Children with Renal Anemia.- Bone Marrow Erythroid Precursor Cytoplasmic Ca2+ and 1, 25-Dihydroxyvitamin D3 Regulate the Response to Human Recombinant Erythropoietin in Uremia: In Vitro and In Vivo Studies.- Dyserythropoietic Abnormalities in Hemodialysis Patients on Long-Term Therapy with Human Recombinant Erythropoietin.- Cardiological Findings in Patients with End-Stage Renal Failure Under Treatment with Erythropoietin.- Long-Term Treatment with Recombinant Human Erythropoietin inlsO