Provides an accessible guide to the dissection and perfusion of rats, placing particular emphasis on the preparation of nervous tissue for further study in the laboratory including biochemical analysis and microscopic study. Logically structured with highly illustrated chapters, the book provides a comprehensive introduction to those techniques required to provide consistent, high-quality tissues for subsequent investigation. An overview of the essential topics of animal husbandry of a high standard and minimisation of discomfort is also incorporated.Gross Anatomy.
Anatomy of the Nervous System.
Anaesthesia.
Biological Fixation.
Brain Extraction.
Extraction of Selected Cranial Nerves, Intact Spinal Cord and Sciatic Nerves.
Appendices.
Glossary.
Bibliography.
Index.
J. P. Cassella is the author of The Rat Nervous System: An Introduction to Preparatory Techniques, published by Wiley.
J. Hay is the author of The Rat Nervous System: An Introduction to Preparatory Techniques, published by Wiley.
S. J. Lawson is the author of The Rat Nervous System: An Introduction to Preparatory Techniques, published by Wiley.
The Rat Nervous System An Introduction to Preparatory Techniques J. P. Cassella Institute of Psychiatry, London, UK J. Hay Tennant Institute of Ophthalmology, University of Glasgow, UK and S. J. Lawson Imperial College School of Medicine at St Mary's, London, UK For over thirty years, rodents have been used in the study of many human and animal diseases. The rat in particular continues to serve as an experimental model for drug safety and efficacy tests for the treatment of neurological disorders, heart disease, diabetes, breast, liver and other cancers. With the more recent advent of transgenic technology, an l³&